Lactoferrin Inhibits Enterovirus 71 Infection of Human Embryonal Rhabdomyosarcoma Cells In Vitro
نویسندگان
چکیده
منابع مشابه
Lactoferrin inhibits enterovirus 71 infection of human embryonal rhabdomyosarcoma cells in vitro.
Enterovirus 71 (EV71), the newest member of Enterovirudae, is notable for its etiological role in epidemics of severe neurological diseases in children. It appears to be emerging as an important virulent neurotropic enterovirus in the upcoming era of poliomyelitis eradication, whereas no effective vaccine or antiviral agents are available at this moment. Human and bovine lactoferrins, iron-bind...
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BACKGROUND Enterovirus 71 (EV71) infection can induce the apoptosis of infected cells. The aim of this study is to explore the effect of EV71 infection on apoptosis mechanisms in virus-infected human rhabdomyosarcoma (RD) cells. METHODS The apoptosis of RD cells was examined using annexin V-FITC/PI by flow cytometry and cytokines were detected by ELISA. Cellular RNA was extracted and transcri...
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ژورنال
عنوان ژورنال: The Journal of Infectious Diseases
سال: 2002
ISSN: 0022-1899,1537-6613
DOI: 10.1086/343809